Current perspective on treating herpes zoster and postherpetic neuralgia
نویسندگان
چکیده
منابع مشابه
Treating Herpes Zoster and Postherpetic Neuralgia
Michael C. Rowbotham, MD California Pacific Medical Center Research Institute Department of Anesthesia, UCSF School of Medicine San Francisco, Calif., USA Email: [email protected] P ostherpetic neuralgia (PHN) is t e most frequent chronic complication of herpes zoster ( hingles). Herpes zoster (HZ) represents a reactivation of the varicella zo ter vi us (VZV), a ubiquitous, highly neurotropic,...
متن کاملHerpes zoster and postherpetic neuralgia.
Herpes zoster (HZ; shingles) results from reactivation of varicella-zoster virus that has been dormant in the spinal and cranial sensory ganglia following primary infection with varicella (chickenpox), usually during childhood. In developed countries more than 95% of the adult population are seropositive for varicella-zoster virus and are therefore at risk of developing HZ. Reactivation can occ...
متن کاملHerpes zoster and postherpetic neuralgia.
Pain associated with herpes zoster arise from the virul neuritis of the suffered trigeminal or spinal dorsal ganglion. Prolonged neuritis makes an irreversible nerve injury and continuous pain impulse develops a central sensitization. A post-herpetic neuralgia is thought to be a neuropathic pain due to the irreversible nerve injury and sensitization. It is important to treat herpetic pain compl...
متن کاملVaccination against Herpes Zoster and Postherpetic Neuralgia.
BACKGROUND Herpes zoster (HZ) and postherpetic neuralgia (PHN) cause significant morbidity in older adults. The incidence and severity of HZ and PHN increase with age in association with an age-related decline in varicella-zoster virus (VZV)-specific cell-mediated immunity (VZV-CMI). VZV vaccines can boost VZV-CMI. Therefore, we tested the hypothesis that VZV vaccination would protect older adu...
متن کاملManaging herpes zoster and postherpetic neuralgia.
Treatment strategies for herpes zoster infection include limiting viral replication with anti-infective agents as well as limiting associated acute and chronic neuropathic pain with a variety of analgesics. The author outlines currently available pharmacotherapeutic options, from first-line (eg, anti-infective agents, tricyclic antidepressants, anticonvulsants, opioid analgesics, and topical ag...
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ژورنال
عنوان ژورنال: Dermatologie pro praxi
سال: 2018
ISSN: 1802-2960,1803-5337
DOI: 10.36290/der.2018.043